Formative and Pilot Intervention Research for Prevention and Treatment of HIV/AIDS (R34) | PA 17 166

Opportunity Information: Apply for PA 17 166

Formative and Pilot Intervention Research for Prevention and Treatment of HIV/AIDS (R34) is a National Institutes of Health (NIH) grant opportunity designed to support early-stage work that helps promising HIV interventions get ready for larger, definitive trials. The emphasis is on formative research, intervention development, and pilot testing, meaning applicants are expected to refine an intervention concept, test whether it can realistically be delivered as intended, and generate the preliminary evidence needed to justify a subsequent, bigger study. The program is especially aimed at learning whether a new or adapted intervention is feasible to implement in a real-world setting, whether people can tolerate it, whether the intended users and stakeholders find it acceptable, and whether it can be delivered safely.

Within this announcement, an "intervention" is defined broadly. It can be behavioral, social, or structural, and it can also be a combination approach that includes biomedical components alongside behavioral, social, or structural strategies. The intervention may focus on preventing HIV acquisition and transmission, improving clinical outcomes for people living with HIV, or addressing both prevention and treatment together. In practice, this scope allows for a wide range of projects, such as adapting an evidence-based behavioral program for a new population, developing a community or health-system strategy that removes barriers to prevention tools, testing the usability and safety of a technology-assisted adherence approach, or piloting a combination package that pairs biomedical prevention or treatment with supportive social or behavioral components.

The opportunity is listed as a discretionary grant (Funding Instrument Type: Grant) in the health funding category, with CFDA number 93.242. The funding opportunity number is PA-17-166, and the source data indicates an award ceiling of $225,000. The original closing date shown is 2018-01-24, and the record creation date is 2017-02-13, which signals that the specific posting referenced is from that time period and may now be historical or part of a broader continuing NIH program line.

Eligibility is intentionally broad and includes many types of U.S. and non-U.S. organizations that can credibly carry out public health research. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; and public housing authorities/Indian housing authorities. Academic institutions are eligible, including public and state-controlled institutions of higher education and private institutions of higher education. Tribal entities and organizations can apply, including federally recognized Native American tribal governments and Native American tribal organizations other than federally recognized tribal governments. Nonprofits are eligible whether or not they have 501(c)(3) status (as long as they are not institutions of higher education in that category), and both for-profit organizations (other than small businesses) and small businesses may apply. The announcement also highlights additional eligible applicants such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and non-domestic (non-U.S.) entities (foreign organizations).

Overall, the R34 mechanism here is geared toward reducing risk before major investment in a full-scale efficacy or effectiveness study. A competitive project under this announcement would typically present a clear HIV prevention and/or treatment challenge, propose a novel or thoughtfully adapted intervention, and include a practical plan for early testing that produces concrete information about implementation feasibility, participant and provider acceptability, tolerability, and safety, along with the operational lessons needed to scale the work into a larger trial or broader public health application.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Formative and Pilot Intervention Research for Prevention and Treatment of HIV/AIDS (R34)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242.
• This funding opportunity was created on 2017-02-13.
• Applicants must submit their applications by 2018-01-24. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $225,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

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