Opportunity Information: Apply for CDC RFA GH20 2068

This funding opportunity, issued by the U.S. Department of Health and Human Services through the Centers for Disease Control and Prevention (CDC), focuses on strengthening the capacity and coordination of civil society organizations (CSOs) in Uganda to speed up HIV epidemic control among key populations under PEPFAR. It is structured as a cooperative agreement, meaning the CDC expects to have substantial involvement in the work alongside the recipient(s), rather than simply providing a grant with minimal interaction. The overall intent is to improve how community-based and rights-oriented organizations work with government and major implementing partners so that key populations can access comprehensive HIV prevention and treatment services more consistently and effectively.

The program is grounded in PEPFAR priorities around human rights and the principle of leaving no one behind. In Uganda, key populations such as female sex workers, men who have sex with men, people who inject drugs, transgender people, and people in prison settings account for a meaningful share of new HIV infections (noted in the opportunity as more than 7% of new infections). Despite their disproportionate risk, services tailored to these groups are described as insufficient in coverage, quality, and coordination. The opportunity argues that better-resourced and better-coordinated CSOs are essential to closing these gaps because they often have direct trust-based access to key populations, can address stigma and discrimination, and can help clients navigate complex health and social systems.

The core of the work is to build CSO capacity so these organizations can collaborate more effectively with CDC-funded implementing partners, Uganda's Ministry of Health, and other relevant government ministries. A major emphasis is improving end-to-end service delivery for key populations, including HIV prevention, HIV testing and case identification, linkage to care, timely initiation of antiretroviral therapy, adherence support, and achieving viral load suppression. The opportunity also highlights strengthening referral pathways, especially those that connect community-based partners and outreach programs to clinical services and follow-up support. In practical terms, this implies improving coordination mechanisms, strengthening operational systems, and ensuring that key population clients do not fall through gaps between outreach, testing, treatment initiation, and long-term retention.

Another central element is addressing the legal, policy, and structural barriers that make it difficult for key populations to access services. While the notice does not list specific interventions line by line, it clearly indicates that the award is meant to support work that reduces obstacles such as stigma, discrimination, and other structural constraints that interrupt access to comprehensive HIV services. This focus reflects a recognition that biomedical services alone are not enough if key populations avoid clinics, cannot safely seek care, or face institutional barriers that delay or prevent treatment and prevention uptake.

The approach builds on prior PEPFAR investments, specifically lessons learned from the Local Capacity Initiative and the Key Population Investment Fund. By referencing these earlier efforts, the opportunity signals an intention to scale or refine strategies that have already been tested, rather than starting from scratch. It also places strong weight on coordinated engagement across major stakeholders, with recipients expected to work alongside relevant PEPFAR agencies, the Global Fund to Fight AIDS, Tuberculosis and Malaria, the Ministry of Health, CDC implementing partners, and other stakeholders. The overall goal is to spearhead more effective engagement of key population-focused CSOs within the national HIV response so that services become more accessible, better linked, and more responsive to the realities faced by these communities.

In terms of funding and administrative details, this opportunity is listed under CFDA 93.067 and categorized as a health-related discretionary funding program. The approximate total funding anticipated for the first year is $2,000,000, subject to the availability of funds. The notice lists an award ceiling for Year 1 as $0, which typically indicates that the CDC is not setting a maximum cap per award in the posting, rather than implying that no funding will be provided. The CDC expected to make two awards. Eligibility is described as unrestricted, meaning it is broadly open to many entity types as long as any specific eligibility clarifications in the full announcement are met. The funding opportunity number is CDC RFA GH20-2068. It was created January 9, 2020, with an original application deadline of March 9, 2020, and electronic submissions due by 11:59 p.m. Eastern Time on the closing date.

Overall, the opportunity is designed to strengthen the ecosystem of community-led and community-connected organizations serving key populations in Uganda, improve coordination with government and large implementing partners, and translate those improvements into better HIV prevention and treatment outcomes, particularly earlier diagnosis, faster ART initiation, stronger adherence, and higher viral suppression. The larger strategic aim is accelerated epidemic control that explicitly includes people who are often hardest to reach and most affected by structural barriers to care.

  • The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Strengthening Civil Society Organizations' Capacity and Coordination for Accelerated HIV Epidemic Control in Uganda through Supporting Implementation of Comprehensive HIV/AIDS Prevention and Treatment for Key Populations (KP) under PEPFAR" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
  • This funding opportunity was created on Jan 09, 2020.
  • Applicants must submit their applications by Mar 09, 2020 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 2 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for CDC RFA GH20 2068

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Frequently Asked Questions (FAQs)

What is the purpose of this funding opportunity?

This opportunity supports efforts to strengthen the capacity and coordination of civil society organizations (CSOs) in Uganda so they can help speed up HIV epidemic control among key populations under PEPFAR. The overall intent is to improve how community-based and rights-oriented organizations work with government and major implementing partners so key populations can access comprehensive HIV prevention and treatment services more consistently and effectively.

Which U.S. agency is issuing this opportunity?

The opportunity is issued by the U.S. Department of Health and Human Services (HHS) through the Centers for Disease Control and Prevention (CDC).

What type of award is this?

This is a cooperative agreement. That means CDC expects substantial involvement in the work alongside the recipient(s), rather than providing funding with minimal ongoing interaction.

What country and communities are the focus of the program?

The program focuses on Uganda and is specifically aimed at improving HIV outcomes among key populations. The notice highlights that key populations account for a meaningful share of new HIV infections in Uganda (noted as more than 7% of new infections).

Which groups are considered "key populations" in this opportunity?

The opportunity identifies key populations as female sex workers, men who have sex with men, people who inject drugs, transgender people, and people in prison settings.

Why does the opportunity emphasize CSOs?

The opportunity explains that CSOs often have direct, trust-based access to key populations and can help address stigma and discrimination, support client navigation through complex systems, and close gaps in coverage, quality, and coordination of services tailored to key populations.

What are the main program priorities and principles?

The program is grounded in PEPFAR priorities around human rights and the principle of leaving no one behind, with a focus on ensuring key populations can access comprehensive, coordinated HIV services.

What kinds of HIV services and outcomes are emphasized?

The opportunity emphasizes improving end-to-end service delivery for key populations, including HIV prevention, HIV testing and case identification, linkage to care, timely initiation of antiretroviral therapy (ART), adherence support, and achieving viral load suppression.

What does "end-to-end service delivery" mean in this context?

Based on the notice, it refers to improving the full pathway from outreach and prevention through testing, case identification, linkage to care, ART initiation, adherence support, and long-term retention leading to viral load suppression, with fewer gaps between community-based activities and clinical services.

How does this opportunity address coordination problems?

It prioritizes building CSO capacity so organizations can collaborate more effectively with CDC-funded implementing partners, Uganda's Ministry of Health, and other relevant government ministries. It also highlights strengthening referral pathways that connect community outreach and follow-up support to clinical services.

What are "referral pathways" and why are they important here?

Referral pathways are the mechanisms that connect clients from community-based outreach and testing to clinical services and follow-up support. The opportunity treats strengthened referral pathways as critical to preventing clients from falling through gaps between testing, treatment initiation, and long-term retention.

Does the opportunity include work on stigma, discrimination, or structural barriers?

Yes. A central element is addressing legal, policy, and structural barriers that interrupt access to comprehensive HIV services for key populations. The notice indicates the award is meant to support work that reduces obstacles such as stigma, discrimination, and other structural constraints.

Are specific interventions listed in the notice?

The notice does not provide a line-by-line list of specific interventions in the provided description, but it clearly indicates emphasis on capacity building, coordination, referral strengthening, end-to-end service improvements, and reducing structural barriers that block access to services.

Who are recipients expected to coordinate with?

Recipients are expected to work alongside relevant PEPFAR agencies, the Global Fund to Fight AIDS, Tuberculosis and Malaria, Uganda's Ministry of Health, CDC implementing partners, other relevant government ministries, and other stakeholders involved in the national HIV response.

How does this opportunity relate to prior PEPFAR investments?

The approach builds on lessons learned from prior PEPFAR investments, specifically the Local Capacity Initiative and the Key Population Investment Fund. This signals an intention to scale or refine strategies that have already been tested rather than starting from scratch.

What is the CFDA number for this opportunity?

The opportunity is listed under CFDA 93.067.

How is this opportunity categorized?

It is categorized as a health-related discretionary funding program.

How much funding is anticipated?

The approximate total funding anticipated for the first year is $2,000,000, subject to the availability of funds.

How many awards does CDC expect to make?

CDC expected to make two awards.

Is there an award ceiling (maximum) for Year 1?

The notice lists an award ceiling for Year 1 as $0. In this context, it typically indicates CDC is not setting a maximum cap per award in the posting, rather than implying that no funding will be provided.

Who is eligible to apply?

Eligibility is described as unrestricted, meaning it is broadly open to many entity types, as long as any specific eligibility clarifications in the full announcement are met.

What is the funding opportunity number?

The funding opportunity number is CDC RFA GH20-2068.

When was the opportunity created and when were applications due?

The opportunity was created on January 9, 2020. The original application deadline was March 9, 2020, with electronic submissions due by 11:59 p.m. Eastern Time on the closing date.

What is the overarching goal of the program?

The overarching goal is accelerated HIV epidemic control in Uganda that explicitly includes key populations who are often hardest to reach and most affected by structural barriers to care, translating stronger community-led capacity and coordination into earlier diagnosis, faster ART initiation, stronger adherence, and higher viral suppression.

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