Opportunity Information: Apply for PAR 17 189
The National Institutes of Health (NIH) grant opportunity titled "Translational Research in Pediatric and Obstetric Pharmacology and Therapeutics (R01)" (Funding Opportunity Number PAR-17-189) supports research aimed at improving how medications are studied, used, and developed for two populations that are often underserved by traditional drug research: children across different stages of development and women during pregnancy and lactation. The FOA is designed to fund translational and clinical research, including clinical trials, that can clarify how drugs work in the body, why patients respond differently, and what drives safety concerns in these groups. At its core, the program is focused on generating evidence that can lead to safer and more effective therapies, whether that means optimizing the use of medications that are already on the market or helping move new therapies forward in a way that better reflects real clinical needs in pediatrics and obstetrics.
A major emphasis of this opportunity is understanding mechanisms of drug action, variability in response, and safety risks in ways that account for biology that is unique to these populations. For pediatrics, that means recognizing that infants, children, and adolescents are not simply smaller adults; developmental changes can affect drug absorption, distribution, metabolism, and elimination, which in turn can change dosing needs and risk profiles over time. For pregnancy and lactation, physiologic changes can significantly alter drug handling and exposure, and there is added complexity in considering fetal exposure during pregnancy and infant exposure through breast milk. The FOA is meant to encourage research that directly tackles these issues, filling gaps that can lead to off-label use, uncertainty in dosing, and preventable adverse events.
Because it is an R01, the mechanism signals support for substantial, hypothesis-driven projects that can produce meaningful advances and are generally suited for multi-year, well-structured research programs. The FOA explicitly welcomes a range of study types, spanning translational work that bridges laboratory insights to patient care, clinical pharmacology studies, and clinical trials when appropriate. The practical outcome the NIH is pushing toward is clearer, evidence-based guidance on how to use existing drugs more safely and effectively in pediatric and obstetric settings, along with research that supports development of new drugs or new approaches to using current drugs in a more tailored, precision-oriented way.
Eligibility for this funding is broad, which is consistent with NIH’s aim to draw in diverse expertise and reach populations that may experience health disparities. Eligible applicants include many types of U.S. governmental entities (state, county, city/township, and special district governments), independent school districts, and tribal governments (including federally recognized tribes), as well as public housing authorities/Indian housing authorities. Academic eligibility includes public and state-controlled institutions of higher education and private institutions of higher education. The FOA also allows nonprofit organizations both with and without 501(c)(3) status, and it permits for-profit organizations (other than small businesses) and small businesses. In addition, the announcement highlights that other eligible applicants include Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and even non-U.S. entities (foreign organizations). That broad eligibility suggests the NIH is open to collaborations and settings that can better reach pregnant and lactating people and pediatric populations, including globally, where certain pharmacology questions may be especially pressing.
From an administrative standpoint, the opportunity is categorized as discretionary funding and uses the grant funding instrument. The activity category is listed under Health, Income Security and Social Services, and the CFDA numbers associated with the program are 93.173 and 93.865. The FOA was created on March 3, 2017, and the original closing date listed in the source information is July 3, 2020. Some fields in the source data, such as the award ceiling and expected number of awards, are not specified, which is common in NIH announcements where budgets and award counts may depend on application quality, availability of funds, and program priorities.
Overall, this FOA is best understood as an NIH effort to strengthen the scientific foundation behind medication use in children and in pregnancy/lactation by funding research that can explain drug behavior and drug effects in these settings, quantify and predict safety risks, and translate findings into better treatment strategies. The intended impact is tangible clinical improvement: better dosing, fewer adverse drug events, more confidence in prescribing decisions, and ultimately therapies that are better matched to the real biological and developmental context of pediatric and obstetric patients.Apply for PAR 17 189
- The National Institutes of Health in the health, income security and social services sector is offering a public funding opportunity titled "Translational Research in Pediatric and Obstetric Pharmacology and Therapeutics (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173, 93.865.
- This funding opportunity was created on 2017-03-03.
- Applicants must submit their applications by 2020-07-03. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Apply for PAR 17 189
Applicants also applied for:
Applicants who have applied for this opportunity (PAR 17 189) also looked into and applied for these:
| Funding Opportunity |
|---|
| Translational Research in Pediatric and Obstetric Pharmacology and Therapeutics (R03) Apply for PAR 17 188 Funding Number: PAR 17 188 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $50,000 |
| Human-Animal Interaction (HAI) Research (R21) Apply for PAR 17 229 Funding Number: PAR 17 229 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $200,000 |
| Resource-Related Research Projects in the Epidemiology and Prevention of Pediatric Injury (R24) Apply for PAR 17 228 Funding Number: PAR 17 228 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $375,000 |
| Human-Animal Interaction (HAI) Research (R03) Apply for PAR 17 230 Funding Number: PAR 17 230 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $50,000 |
| Human-Animal Interaction (HAI) Research (R01) Apply for PAR 17 231 Funding Number: PAR 17 231 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $499,999 |
| Development of Appropriate Pediatric Formulations and Pediatric Drug Delivery Systems (R03) Apply for PAR 17 191 Funding Number: PAR 17 191 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $50,000 |
| Development of Appropriate Pediatric Formulations and Pediatric Drug Delivery Systems (R21) Apply for PAR 17 192 Funding Number: PAR 17 192 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $200,000 |
| Development of Appropriate Pediatric Formulations and Pediatric Drug Delivery Systems (R01) Apply for PAR 17 193 Funding Number: PAR 17 193 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Development of Appropriate Pediatric Formulations and Pediatric Drug Delivery Systems (R43) Apply for PAR 17 199 Funding Number: PAR 17 199 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Development of Appropriate Pediatric Formulations and Pediatric Drug Delivery Systems (R41) Apply for PAR 17 200 Funding Number: PAR 17 200 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Identification of Reproductive-Tract Specific Proteins/Transcripts for the Development of Male and Female Non-Hormonal Contraceptives (R01) Apply for RFA HD 18 002 Funding Number: RFA HD 18 002 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Point of Care Technologies for the Evaluation and Management of Obstetrics, Neonatal, and Pediatric Critical Care Patients, and for Patients with Disorders of Reproductive Tract and Infertility (R43) Apply for RFA HD 18 028 Funding Number: RFA HD 18 028 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| NICHD Exploratory-Developmental Research Grant (R21) Apply for PA 17 259 Funding Number: PA 17 259 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $200,000 |
| Promoting NICHD Areas of Research for HIV/AIDS in Maternal and Child Health (R01) Apply for PA 17 262 Funding Number: PA 17 262 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Data Coordinating Center for the NICHD Neonatal Research Network (U24) Apply for RFA HD 18 010 Funding Number: RFA HD 18 010 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Small Grants for Secondary Analyses of Existing Data Sets and Stored Biospecimens (R03) Apply for PA 17 299 Funding Number: PA 17 299 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $50,000 |
| Re-Competition of Global Network for Womens and Childrens Health Research (UG1) Apply for RFA HD 18 009 Funding Number: RFA HD 18 009 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Population Dynamics Centers Research Infrastructure Program FY 2018 (P2C) Apply for RFA HD 18 013 Funding Number: RFA HD 18 013 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| National Centers for Translational Research in Reproduction and Infertility (P50) Apply for RFA HD 18 008 Funding Number: RFA HD 18 008 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Typical and Atypical Patterns of Language and Literacy in Dual Language Learners (R01) Apply for PA 17 443 Funding Number: PA 17 443 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $500,000 |
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