Opportunity Information: Apply for CDC RFA GH21 2147
This funding opportunity, titled "Strengthening Systems to Improve HIV Service Delivery and Other Public Health Interventions Through Continuous Quality Improvement, Monitoring and Evaluation, Surveillance, Health Informatics and Laboratory Quality Management in Nigeria under PEPFAR" (CDC RFA GH21 2147), is a CDC cooperative agreement focused on reinforcing Nigeria's health systems so HIV and other public health programs can be managed and delivered more effectively and with consistently higher quality. The intent is to consolidate gains already made under PEPFAR and help Nigeria sustain progress toward HIV epidemic control by improving the underlying systems that support prevention, care and treatment, data use, and laboratory performance.
The program centers on several connected health system strengthening areas: Continuous Quality Improvement (CQI), Monitoring and Evaluation (M&E), surveillance, health informatics, and laboratory quality management. Rather than funding direct service delivery alone, the emphasis is on building the infrastructure and routines that make service delivery reliable, measurable, and continuously improvable. A major component is implementing evaluations and surveys that examine performance across the HIV program cascade, including prevention, clinical care and treatment, and laboratory management, with attention to both the general population and key populations. These evaluation activities are meant to identify gaps, test what is working, and guide program adjustments using evidence rather than assumptions.
A core deliverable for recipient organizations is developing and rolling out a practical framework to mainstream CQI and data quality assessment and improvement (DQA/I) in PEPFAR-supported health facilities. This implies helping facilities and implementing partners move beyond one-off quality projects to routine quality management: standard indicators, consistent data checks, structured problem-solving, and repeated improvement cycles that are integrated into everyday operations. The work is designed to be collaborative, carried out in coordination with comprehensive service delivery partners operating in PEPFAR-supported sites, so that quality improvement approaches are aligned with how services are actually delivered and reported.
Another major focus is strengthening national governance and systems for health information and informatics. Recipients are expected to support the host government in developing governance frameworks that improve how health information systems are managed, aligned, and sustained. This includes supporting the implementation and ongoing maintenance of key digital health platforms that underpin HIV program monitoring and clinical management, including the National Data Repository (NDR), Electronic Medical Records (EMR) systems, and Laboratory Information Management Systems (LIMS), among others. The overall direction is to improve data availability, interoperability, reliability, and use for decision-making at facility, state, and national levels, so program leaders can track performance, detect problems early, and target resources where they are most needed.
Laboratory systems are treated as a critical backbone of HIV service delivery, so the opportunity also supports laboratory quality management, including activities aimed at accreditation and strengthening quality systems. This reflects the reality that accurate and timely laboratory testing is central to HIV diagnosis, treatment monitoring, and viral load suppression, and that weak lab quality can undermine even well-run clinical programs. By improving laboratory quality management and supporting accreditation pathways, the program aims to raise consistency and confidence in lab results, reduce errors, and improve turnaround times that affect patient care.
From an administrative standpoint, this is a discretionary funding opportunity from the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), under CFDA 93.067, using a cooperative agreement mechanism, which typically means substantial involvement by CDC in technical direction and oversight. Eligibility is listed as unrestricted (open to any type of entity, subject to any additional eligibility clarifications in the full notice). CDC anticipated making two awards. For funding, the notice states that the Year 1 award ceiling is listed as 0 (meaning no fixed ceiling was specified in the posting), while the approximate total funding anticipated for Year 1 was $15,000,000, dependent on availability of funds. The opportunity was posted February 18, 2021, with an original application deadline of April 19, 2021 (11:59 p.m. ET for electronic submissions).
In practical terms, the opportunity is aimed at organizations that can operate at the intersection of program quality, data systems, evaluation, and laboratory strengthening, with the ability to work closely with government counterparts and implementing partners. The overarching outcome is a more durable, better-governed, and data-driven health system that can maintain high-quality HIV services at scale and support broader public health interventions, thereby contributing to Nigeria's ability to achieve and sustain HIV epidemic control.Apply for CDC RFA GH21 2147
- The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Strengthening Systems to Improve HIV Service Delivery and Other Public Health Interventions Through Continuous Quality Improvement, Monitoring and Evaluation, Surveillance, Health Informatics and Laboratory Quality Management in Nigeria under PEPFAR" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
- This funding opportunity was created on Feb 18, 2021.
- Applicants must submit their applications by Apr 19, 2021 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Frequently Asked Questions (FAQs)
1) What is the title and reference number of this funding opportunity?
The opportunity is titled "Strengthening Systems to Improve HIV Service Delivery and Other Public Health Interventions Through Continuous Quality Improvement, Monitoring and Evaluation, Surveillance, Health Informatics and Laboratory Quality Management in Nigeria under PEPFAR" with reference number CDC RFA GH21 2147.
2) Who is offering this opportunity?
This is a U.S. Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC) funding opportunity.
3) What type of award mechanism is used?
The mechanism is a CDC cooperative agreement, which typically involves substantial CDC involvement in technical direction and oversight.
4) What is the CFDA number associated with this opportunity?
The CFDA number listed is 93.067.
5) What is the main purpose of the program?
The purpose is to reinforce Nigeria's health systems so HIV and other public health programs can be managed and delivered more effectively and with consistently higher quality, consolidating gains under PEPFAR and supporting progress toward HIV epidemic control.
6) Is this opportunity focused on Nigeria?
Yes. The work is framed around strengthening systems in Nigeria in support of PEPFAR-supported HIV programming and related public health interventions.
7) What program areas does the opportunity emphasize?
The opportunity centers on connected health system strengthening areas: Continuous Quality Improvement (CQI), Monitoring and Evaluation (M&E), surveillance, health informatics, and laboratory quality management.
8) Does the opportunity fund direct service delivery?
The emphasis is not on direct service delivery alone. The focus is on building the underlying infrastructure and routines that make service delivery reliable, measurable, and continuously improvable.
9) What is meant by Continuous Quality Improvement (CQI) in this program?
CQI is framed as moving beyond one-off quality projects toward routine quality management in facilities, including standard indicators, consistent data checks, structured problem-solving, and repeated improvement cycles integrated into everyday operations.
10) What is Data Quality Assessment/Improvement (DQA/I) and how does it fit here?
A core deliverable is developing and rolling out a practical framework to mainstream CQI and data quality assessment and improvement (DQA/I) in PEPFAR-supported health facilities, supporting consistent data checks and ongoing data improvement as part of routine operations.
11) What evaluations and surveys are expected under this opportunity?
The program includes implementing evaluations and surveys that examine performance across the HIV program cascade, including prevention, clinical care and treatment, and laboratory management.
12) Which populations are considered in the evaluation activities?
The evaluation activities are described as covering both the general population and key populations.
13) What is the goal of the evaluations and surveys?
The evaluations are meant to identify gaps, test what is working, and guide program adjustments using evidence rather than assumptions.
14) What does "mainstreaming" CQI and DQA/I in facilities imply in practice?
It implies helping facilities and implementing partners adopt routine, integrated approaches to quality and data management, rather than treating quality improvement as occasional or standalone activities.
15) Is coordination with other partners expected?
Yes. The work is intended to be collaborative and carried out in coordination with comprehensive service delivery partners operating in PEPFAR-supported sites, aligning quality improvement approaches with how services are delivered and reported.
16) What is the health informatics and governance focus of the award?
Recipients are expected to support the host government in developing governance frameworks that improve how health information systems are managed, aligned, and sustained.
17) Which digital health platforms are specifically mentioned?
The notice references supporting implementation and ongoing maintenance of key digital health platforms including the National Data Repository (NDR), Electronic Medical Records (EMR) systems, and Laboratory Information Management Systems (LIMS), among others.
18) What outcomes are expected from strengthening health information systems?
The stated direction is improving data availability, interoperability, reliability, and use for decision-making at facility, state, and national levels so leaders can track performance, detect problems early, and target resources where they are most needed.
19) Why is laboratory quality management included?
Laboratory systems are treated as a critical backbone of HIV service delivery because accurate and timely testing supports HIV diagnosis, treatment monitoring, and viral load suppression, and weak lab quality can undermine clinical programs.
20) What laboratory-related activities does the opportunity support?
The opportunity supports laboratory quality management, including activities aimed at accreditation and strengthening quality systems, with the intent to improve consistency and confidence in lab results, reduce errors, and improve turnaround times that affect patient care.
21) What is the broader public health relevance beyond HIV?
While HIV service delivery under PEPFAR is central, the opportunity also targets "other public health interventions" by strengthening the underlying systems (quality management, surveillance, informatics, laboratories) that can support broader health programs.
22) What kind of organizations is this opportunity aimed at?
In practical terms, it is aimed at organizations able to operate at the intersection of program quality, data systems, evaluation, and laboratory strengthening, and able to work closely with government counterparts and implementing partners.
23) What is the stated eligibility for applicants?
Eligibility is listed as unrestricted, meaning it is open to any type of entity, subject to any additional eligibility clarifications in the full notice.
24) How many awards did CDC anticipate making?
CDC anticipated making two awards.
25) What was the anticipated funding amount for Year 1?
The approximate total funding anticipated for Year 1 was $15,000,000, dependent on the availability of funds.
26) Was there a stated ceiling (maximum) award amount for Year 1?
The Year 1 award ceiling was listed as 0, which in the posting is presented as meaning no fixed ceiling was specified.
27) When was the opportunity posted?
The opportunity was posted on February 18, 2021.
28) What was the application deadline?
The original application deadline was April 19, 2021, with electronic submissions due by 11:59 p.m. ET.
29) What is the intended end result of the funded work?
The overarching outcome described is a more durable, better-governed, and data-driven health system that can maintain high-quality HIV services at scale and support broader public health interventions, contributing to Nigeria's ability to achieve and sustain HIV epidemic control.
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